GNS Healthcare Blog

GNS Healthcare Blog

GNS Healthcare Primary Blog

By December 31, 1969

Disorganizing Principles: Why Healthcare is Broken and How to Fix It

“How often have pharma, insurance and provider leaders thought about the ‘organizing principles’ around healthcare?”

That’s a question posed by Greg Simon, President of the Biden Cancer Initiative, at the recent GNS Precision Medicine Forum. His answer? Not enough. That was the overarching message of his presentation to the gathered group of healthcare industry leaders.

Organizing principles, the guiding ideas used to direct a society, organization or initiative are important because they create the framework and provide a consistent direction that propels a company, entity or industry...

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Celebrating a healthcare revolution

Happy Fourth of July – a day we celebrate the birth of our nation. A day we recognize and applaud our country’s founders who were bold and progressive thinkers. A day to be grateful for  the establishment of the United States and its founding principles which have weathered the test of time.

The path to revolution is one familiar to the pioneers of healthcare: slow to change, rife with internal disagreement and peppered by a number of fits and starts. If it sounds familiar, it should. The push for change and efficiency has been propelling new advancements in healthcare. Instead of throwing...

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Today's FDA: How We Got Here


The FDA's role has always been to balance safety and efficacy when it comes to approving drugs, medical devices and biological products.  And yet the numbers are staggering, to bring a drug to market costs on average $2.7B and takes close to a decade. So how did we get here and what does the future hold? For this blog we take a look back at how the FDA came to be, how Dr. Scott Gottlieb's tenure as FDA Commissioners modernized the FDA, and some speculations for what the future holds.

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Paving the Way for Orphan Drugs with AI and Data

Chances are, you know of someone who suffers from multiple myeloma, non-Hodgins lymphoma or multiple-sclerosis. Despite the familiarity of those conditions, all three are considered rare-diseases by the U.S. Food and Drug Administration (FDA) because they affect less than 200,000 people in the U.S.[1]

According to estimates by the National Institute of Health, there may be as many as 7,000 rare diseases affecting approximately 25-35 million Americans.[2]   So what do rare diseases have to do with AI?  

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Successful Use of AI in Real-World Drug Discovery? It’s All About the Data

Albert Einstein is quoted as saying, "in the middle of difficulty lies opportunity." With the surge of healthcare data we have a great opportunity healthcare in a way not seen before. But, it is well known that using flawed data produces unreliable outputs.  Given the breadth and depth of data that grows daily and the power of  artificial  intelligence (AI) – how do we leverage both to impact how drugs are discovered and developed?

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ASCO, BIO, Forum...Oh My!

Spring is the season of renewal, growth and new beginnings. It is also the time when the healthcare community gets together at key conferences to exchange ideas, findings and results. This year is no different with three major gatherings scheduled for May and June. Discussion of oncology and artificial intelligence are high on the agendas of all three events. Here's a rundown of what to look out for.

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Celebrating Memorial Day - How Healthcare Has Evolved Both On and Off the Battlefield

Memorial Day, the day that honors the men and women who died while serving in the military, traces its roots to the Civil War.  The Civil War claimed more American lives than any other war, prompting the creation of the first national cemeteries. Shortly after, cities and towns across America began honoring the fallen by laying flowers and holding ceremonies at these cemeteries during the spring.  As we honor those who gave their lives, we thought we would take a look back at the past 150 years to see how healthcare has evolved to better care for the military and those they protect.

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Untangling the Mystery of Migraine Progression with AI

Last summer, GNS Chief Commercial Officer and Co-Founder Iya Khalil wrote about the difficulty of watching her sister suffer through the devastating impact of migraine headaches.  Researchers continue to seek therapies and treatments to help mitigate this widespread condition and recent discoveries hold out hope that progress is being made.

More than 39 million people in the U.S. and nearly a billion people worldwide suffer from migraines with about two percent of those being chronic cases. Even more impactful is that migraines are the third most prevalent and the sixth most debilitating...

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The Unlikely Marriage of Statistical Significance and...Uncertainty

National Chocolate Day: Ten Convincing Reasons You Should Eat More of the Stuff, The Telegraph, October 2016

No, Dark Chocolate Is Not a Health Food, Healthline, December 2018New Harvard study finds a glass of wine every day can have huge health benefits, Fox6 Milwaukee, December 2018No Amount of Alcohol Is Good for Your Health, Global Study Says, NPR, August 2018

Why do contradictory headlines like these continually pop up, highlighting the uncertain nature of scientific studies and raising confusion as to what is or isn’t good for us? Blame it on the relative ease and dependence on the...

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If at First You Don’t Succeed…Learn from Clinical Trial Failures


The oft-told story is that it took Thomas Edison’s 10,000 attempts to perfect the invention of the light bulb. He is famously quoted as saying of his many prior unsuccessful efforts, “I have not failed. I’ve just found 10,000 ways that won’t work.”

There is an ongoing discussion as to whether the biopharma industry should adopt a similar attitude when it comes clinical trials. A recent article in BioCentury outlined the clinical trial tug-of-war between traditional frequentists and Bayesians who have been making their way into the arena, starting first in the medical devices field....

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